Garry Shandling died on Thursday at a Los Angeles hospital, The Associated Press reports.
According to TMZ, the 66-year-old comedian suffered a massive heart attack. However, LAPD officer Tony Im told the AP that Shandling died of an undisclosed cause.
Best known for the TV series "The Larry Sanders Show" and "It's Garry Shandling's Show," the Emmy-winning actor racked up dozens of nominations and accolades throughout his lengthy career.